Which of the Following Best Describe the Mechanism of Calmodulin

question 22

Multiple Choice

Which of the following best describe the mechanism of calmodulin (CaM) mediated activation?

• A)Ca²⁺ binding to calmodulin (CaM)results in conformational change that exposes a hydrophobic patch capable of binding to calcium sensitive protein kinase
• B)a conformational change induced by the binding of Ca²⁺ results in the release of the phosphate group in calmodulin (CaM)
• C)calmodulin (CaM)sensitive protein kinase dimerizes forming a joint active site capable of tightly binding Ca²⁺
• D)phosphorylation of a tyrosine on calmodulin induced a conformational change that results in release of Ca²⁺ from the cytosol.
• E)none of the above.

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