Consider the Following Metabolic Reaction Important in Muscle and Nerve $\leftrightarrows$

question 48

Multiple Choice

Consider the following metabolic reaction important in muscle and nerve cells:
ATP + creatine $\leftrightarrows$ phosphocreatine + ADP $\Delta$ G°' = +12.6 kJ/mol
Under intracellular conditions,the $\Delta$ G for the reaction,which is catalyzed by the enzyme creatine kinase,is ~0 kJ/mol.From this information we can conclude that

• A)creatine kinase catalysis would not be necessary under intracellular conditions.
• B)ATP has a greater phosphoryl group transfer potential compared to phosphocreatine.
• C)at equilibrium,most intracellular creatine is phosphorylated.
• D)the reaction operates close to equilibrium in cells.
• E)None of the above is a correct conclusion.

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