How Does the Transcriptional Machinery Gain Access to the Nucleosome-Sequestered

question 14

Multiple Choice

How does the transcriptional machinery gain access to the nucleosome-sequestered DNA?
(I) Methylation of DNA prevents histone binding.
(II) Chromatin-remodeling complexes allow sections of DNA to be transiently exposed to transcription factors.
(III) The transcription proteins have higher affinity for DNA and push the histones away from binding sites.

• A)I,II,III
• B)I,II
• C)II,III
• D)I,III
• E)II only

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