A Patient Is Hospitalized with a Central Nervous System Infection

question 28

Multiple Choice

A patient is hospitalized with a central nervous system infection that needs to be treated with water-soluble antibiotics.The medications will be instilled into the subarachnoid space via an epidural catheter.Why is this the best route of administration for this patient?

• A) Intravenous water-soluble antibiotics cannot pass through the blood-brain barrier.
• B) Only water-soluble medications can pass into the brain and cerebrospinal fluid.
• C) Older patients better tolerate lipid soluble medications than younger patients.
• D) Lipid soluble medications are safer for patients who are pregnant.

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Definitions:

Coefficient Alphas

A statistical measure used to assess the reliability or internal consistency of a test or scale.

Homogeneity

The degree to which a set of elements, such as group members or data points, are similar or uniform in nature.

Reliability Estimates

Statistical measures that assess the consistency or repeatability of a scale, test, or measurement tool over time.

Exploratory Factor Analysis (EFA)

A statistical technique used to identify underlying structures (factors) that explain patterns of correlations within a set of observed variables.