What Is Believed to Be the Underlying Cause of Prion

question 40

Multiple Choice

What is believed to be the underlying cause of prion protein plaque formation?

• A) The PrP^Sc proteins are misfolded and aggregated from PrP^c proteins.
• B) The unstructured N-terminal region of PrP^c is thought to remain unfolded.
• C) The normal PrP^c proteins are aggregated.
• D) The PrP^Sc protein adheres to and inhibits cell membranes.

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Definitions:

High Tide

The maximum height to which water in the ocean rises relative to the land in response to the gravitational pull of the Moon; also refers to the time when such high levels occur.

Low Tide

The lowest height to which water in the ocean drops relative to the land in response to the gravitational pull of the Moon; also refers to the time when such low levels occur.

Spring Tide

A condition of especially high and low tides caused when the sun, moon, and Earth are aligned, increasing the gravitational pull on the oceans.

Neap Tide

A condition of the sea where the difference between high and low tide is at its least, occurring twice a month.