Procathepsin B Is a Lysosomal Protease That Is First Translated

question 21

Multiple Choice

Procathepsin B is a lysosomal protease that is first translated as a proenzyme.On autocleavage it is fully activated.Procathepsin B is

• A) a zymogen.
• B) in the T state after autocleavage.
• C) an allosteric enzyme.
• D) inactive at low pH.

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Definitions:

ATP

Adenosine triphosphate, a molecule that carries energy within cells, essential for various cellular functions.

Mitochondrion

An organelle found in large numbers in most cells, in which the biochemical processes of respiration and energy production occur. It has its own DNA.

Phagocytic Cell

A type of immune cell capable of engulfing and absorbing bacteria, other foreign bodies, and sometimes dead cells.

Macrophage

A macrophage is a type of white blood cell part of the immune system, capable of phagocytosis, engulfing and digesting cellular debris, foreign substances, microbes, and cancer cells.