What Advantage Is There to Phosphoglycerate Kinase Having an Open

question 93

Multiple Choice

What advantage is there to phosphoglycerate kinase having an open and closed configuration?

• A) It allows water to be trapped in the active site along with the substrate.
• B) It forces covalent binding of the substrate to the enzyme active site.
• C) The induced-fit mechanism maximizes accessibility of active site without sacrificing hydrophobic environment.
• D) Changing of the configuration of the enzyme makes the reaction exergonic.

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