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Glutamine-PRPP Amidotransferase Is a Tetrameric Enzyme That Displays Sigmoidal Kinetics

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Glutamine-PRPP amidotransferase is a tetrameric enzyme that displays sigmoidal kinetics when no inhibitors are present.In the presence of either GTP or ATP the kinetics curve is sigmoidal.Why does this difference in kinetics occur?

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Definitions:

Weight Transferred

The act of moving weight or load from one part of the body or an object to another to maintain balance or achieve motion.

Swing-Through Gait

A type of gait pattern used by individuals with lower limb impairments, where crutches or walking devices are placed forward and both legs are swung through.

Immobile

Incapable of moving or being moved.

Supporting Device

An apparatus designed to hold, fix, or support something, especially to aid a person with physical limitations.

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