Mutations in HGPRT Cause Lesch-Nyhan Syndrome

question 25

Essay

Mutations in HGPRT cause Lesch-Nyhan syndrome.Mutations can lead to two different outcomes,both of which result in a reduction of guanine salvaging in cells.Contrast the two classes of mutations in HGPRT that can lead to the same result.

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Definitions:

Bronchus

A major air passage of the lungs that diverges from the windpipe, allowing the flow of air in and out.

Body Surface

The body surface refers to the outermost layer of an organism's body, including the skin in humans, which serves as a protective barrier against the environment.

Tracheal Tubes

A network of air tubes in insects and some terrestrial arthropods that allow for efficient gas exchange directly with body tissues.

Gills

Respiratory organs found in many aquatic organisms, which extract oxygen from water and expel carbon dioxide.