Nirenberg and Matthaei Determined the Genetic Code Experimentally by Using

question 45

Essay

Nirenberg and Matthaei determined the genetic code experimentally by using a cell-free translation system.Two components,however,were restricted in their system.One was the use of a single type of mRNA.What was the other component that was restricted? How did this restriction allow them to determine the genetic code?

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Definitions:

Par

The face value of a bond or other security, at which it can be redeemed at maturity or the amount of money equal in value to a particular share or bond.

Coupon

The yearly payment of interest to those holding bonds, represented as a percentage of the bond's nominal value.

Semi-Annual Coupon

A bond payment made to bondholders twice a year, representing interest on the bond's face value.

Effective Annual Yield

The actual interest rate an investment earns in a year, taking into account the effects of compounding.