A 2-Unit Crossmatch Was Ordered on a Patient in the Emergency

question 35

Multiple Choice

A 2-unit crossmatch was ordered on a patient in the emergency room. The patient's antibody screen was negative. One unit was compatible and the other was incompatible at AHG. If the patient's antibody screen was negative and the donor had no history of antibodies, what could be the reason for this reaction?

• A) The patient's serum has an antibody to a low-frequency antigen not present on screening cells.
• B) The donor has a positive DAT.
• C) The patient's serum has an HTLA antibody.
• D) Options A and B

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