Which of the Following Translocations Results in the Overexpression of the Intact

question 17

Multiple Choice

Which of the following translocations results in the overexpression of the intact translocated gene as opposed to formation of an abnormally functional fusion protein?

• A) t(X;18) in synovial sarcoma
• B) t(2;13) in rhabdomyosarcoma
• C) t(9;22) in chronic myelogenous leukemia
• D) t(14;18) in B-cell chronic lymphocytic leukemia

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Definitions:

Cerebral Cortex

The outermost layer of the brain, involved in high-level functions such as thought, language, memory, and consciousness.

Hearing

The sense by which sound is perceived, involving the detection of vibrations and changes in pressure in the ear.

Sensory Systems

The parts of the nervous system that are involved in receiving and processing sensory information from the environment.

Primary Somatosensory Cortex

The primary somatosensory cortex is a region in the brain that processes tactile information, including sensations of touch, pressure, pain, and temperature.