A Patient Is Tested for the Presence of the Factor

question 23

Multiple Choice

A patient is tested for the presence of the factor V Leiden mutation by PCR-RFLP. The mutation forms a recognition site for the MnlI restriction enzyme. Isolated DNA is amplified by PCR, and the resulting amplicons are cut with MnlI and separated by gel electrophoresis. Two bands are seen in the lane loaded with the patient's sample, one at 153 bp and the other at 67 bp. One band (220 bp) is seen in the normal control. Which of the following is the correct interpretation of these results?

• A) Normal
• B) Heterozygous mutation
• C) Homozygous mutation
• D) Wrong target and method performed for this disease

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Definitions:

American Options

A type of options contract that allows the holder to exercise it at any time before the expiration date.

Call Option

A financial contract giving the buyer the right, but not the obligation, to purchase a stock, bond, or other instrument at a specified price within a specific time period.

Put Option

A financial contract that gives the holder the right, but not the obligation, to sell a specified amount of an underlying asset at a predetermined price within a specified time frame.

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A predetermined price at which goods and services are sold, not subject to change based on fluctuations in market demand or supply.