What Is the Principle of the Acidified Serum Test (Ham's

question 18

Multiple Choice

What is the principle of the acidified serum test (Ham's test) ?

• A) IgM immunoglobulin affixes to RBCs, the classic complement pathway is activated, and the red cells are lysed.
• B) IgG immunoglobulin affixes to RBCs, the alternate pathway is activated, and the RBC is lysed.
• C) Complement affixes to RBCs at acid pH, the alternate pathway is activated, and red cell lysis occurs.
• D) All of the above
• E) None of the above