All of the Following Are Possible Mechanisms for the Pathogenesis

question 25

Multiple Choice

All of the following are possible mechanisms for the pathogenesis in TTP except:

• A) TTP plasma is deficient in a platelet-aggregating factor inhibitor
• B) Large vWF multimers promote platelet agglutination.
• C) Endothelial cell damage via a plasma factor results in platelet adhesion.
• D) Inhibition of cyclo-oxygenase (aspirin-like)
• E) Deficiency of prostacyclin (PGI₂) synthesis and release leading to platelet aggregation and thrombosis

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