Gene Deletions Are the Cause of the Majority of Alpha

question 18

Multiple Choice

Gene deletions are the cause of the majority of alpha thalassemia cases because:

• A) There are no areas of homology between the two closely linked alpha genes globin.
• B) The  ₂ globin gene is expressed at two to three times the rate of  ₁ globin gene.
• C) Great homology in the gene blocks render the areas more susceptible to deletion error during crossover.
• D) Alpha genes are juxtapositioned to numerous transcriptional mutants.
• E) None of the above

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