A 26-Year-Old Day Laborer with a Long History of Anemia

question 22

Multiple Choice

A 26-year-old day laborer with a long history of anemia has a several-month history of dyspnea, fever, and pulmonary pain.Additionally, he complains of tightness in the chest and upper abdominal region.His hematology values are as follows:
WBC 15.9  10⁹/L
RBC 2.9  10¹²/L
Hgb 9.5 g/dL
Hct 30%
MCV 103 fL
MCH 31 pg
MCHC 32%
NRBC 15/100 WBC
Platelets 275  10⁹/L
Reticulocytes 16.8%
The hemoglobin electrophoresis results are as follows:
Hgb A = 3%
Hgb A₂ = 2%
Hgb S = 85%
Hgb F = 10%
The most likely diagnosis is:

• A) Sickle cell trait
• B) Sickle cell disease
• C) Beta thalassemia minor
• D) Sickle thalassemia

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