If a Claisen Condensation Reaction Is Run Using Methyl Propanoate

question 40

Multiple Choice

If a Claisen condensation reaction is run using methyl propanoate as the reactant,NaOCH₃ is the ideal base.Why is it important to use NaOCH₃ and not NaOCH₂CH₃?

• A)NaOCH₃ is a stronger base than NaOCH₂CH₃,and this reaction requires a stronger base.
• B)NaOCH₃ is a weaker base than NaOCH₂CH₃,and this reaction requires a weaker base.
• C)Transesterfication can occur when esters react,and this transesterfication would result in a mixture of products.
• D)NaOCH₃ is more soluble than NaOCH₂CH₃ in organic solvents,and this reaction requires a full equivalent of base to proceed.A full equivalent of NaOCH₂CH₃ would not dissolve,so the reaction would not proceed.

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Definitions:

Nitric Acid

is a strong mineral acid with the formula HNO3, widely used in the manufacture of fertilizers and explosives, as well as in chemical synthesis.

D-Ribose

A naturally occurring five-carbon sugar that is a key component of RNA.

Bromine Water

A solution of bromine in water, used as a reagent to test for the presence of unsaturation in organic compounds.

Monosaccharides

The simplest form of carbohydrates, consisting of single sugar molecules like glucose and fructose, that serve as energy sources.