Transferrin Is a Protein That Binds Iron

question 173

Multiple Choice

Transferrin is a protein that binds iron.It enters cells through transferrin receptors located on the cell membrane.A research group made a mutant transferrin receptor protein by replacing three asparagine residues with glycine.Results of their study are summarized in the table below. Which statement is consistent with these results?

• A) Iron binds to transferrin by recognizing oligosaccharides on the transferrin protein surface.
• B) Iron binds to cells by recognizing oligosaccharides on the transferrin receptor surface.
• C) Transferrin binds to the transferrin receptor protein on the cell surface by recognizing oligosaccharides attached to the receptor.
• D) Asparagine residues provide the critical recognition sites for iron to bind to and enter cells.
• E) Transferrin recognizes asparagine residues on the transferrin receptor protein to bind and enter cells.

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