The Figure Below Shows the Oxytocin Signal Transduction Pathway in Uterine

question 224

Multiple Choice

The figure below shows the oxytocin signal transduction pathway in uterine smooth muscle cells.The abbreviation "CaM" refers to calmodulin, and "MLCK" refers to myosin light chain kinase, an enzyme that phosphorylates the light chains of myosin, stimulating smooth muscle contractions. How could this signal transduction pathway be shut off?

• A) Activate a kinase that phosphorylates phospholipase C, which inactivates it.
• B) Activate an enzyme that degrades DAG.
• C) Add a compound that acts as an agonist of IP₃ with respect to calcium ion channel binding.
• D) Add a compound that acts as an agonist of calcium ion with respect to MLCK activation.
• E) Add a compound that acts as an agonist of oxytocin with respect to oxytocin cell membrane receptor binding.

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