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Phosphofructokinase Catalyzes the First Reaction in a Pathway That Commits

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Phosphofructokinase catalyzes the first reaction in a pathway that commits the product to proceed through glycolysis, often called the first commitment step in glycolysis.Phosphofructokinase is also regulated so that the cell can quickly respond to its energy needs.Given this background information about phosphofructokinase, what is the most likely mode of inactivation of this enzyme when the cell needs to slow down or turn off glycolysis?


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