Refer to the Figure Below, Showing the Flux of Carbon

question 173

Multiple Choice

Refer to the figure below, showing the flux of carbon through metabolic pathways involving both the cytosol and mitochondria in a human muscle cell.The shade of the arrows (light and dark) is proportional to the rate of flux through that pathway. Do you expect this cell to be undergoing rapid contractions or to be inactive, and what do you expect would change as the cell suddenly shifted into the opposite level of activity?

• A) The cell is inactive, and if called into high activity, it would shift metabolism of citrate through the citric acid cycle and electron transport, and away from fatty acid synthesis.
• B) The cell is inactive, and if called into high activity, it would shift metabolism of citrate to synthesis of glucose via gluconeogenesis and away from fatty acid synthesis.
• C) The cell is active, and if the cell became inactive, it would shift metabolism of citrate away from glucose and the citric acid cycle, and toward fatty acid synthesis.
• D) The cell is active, and if the cell became inactive, it would shift metabolism of citrate through the citric acid cycle and electron transport, and away from fatty acid synthesis.
• E) The cell is active, and if the cell became inactive, it would shift citrate toward synthesis of glucose via gluconeogenesis and away from fatty acid synthesis.

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