Refer to the Figure, Showing Allosteric Regulation of Glycolysis and the Citric

question 112

Multiple Choice

Refer to the figure, showing allosteric regulation of glycolysis and the citric acid cycle. If a cell is fed a large supply of fatty acids, which outcome can be expected?

• A) Glycolysis and pyruvate oxidation will be stimulated, causing citrate to build up and activate fatty acid synthase.
• B) Oxidation of fatty acids through the citric acid cycle will be stimulated until ATP builds up and inhibits citrate synthase, diverting fatty acids into storage molecules such as triglycerides.
• C) Glycolysis will be stimulated and pyruvate oxidation will be inhibited as acetyl CoA builds up to high levels in the cell.
• D) The excess fatty acids will deplete the oxygen supply, causing everything except glycolysis to shut down and activating the lactic acid fermentation pathway.
• E) Oxidation of fatty acids to form acetyl CoA will be stimulated, which will stimulate gluconeogenesis to form glucose that the cell can store as an energy resource.

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