An Individual Has a Metabolic Disorder That Is Traced to an Enzyme

question 237

Short Answer

An individual has a metabolic disorder that is traced to an enzyme composed of two different subunits, one larger than the other.The patient has an allele of the smaller subunit that produces a protein that is abnormally large, and when it binds to the other subunit of the enzyme, the enzymatic activity is lost.Analysis of the mRNA sequence identifies a mutation in the 3′ region of a gene that has turned a UAA codon to UUA.Based on this modification, the clinical researcher hypothesizes that during the elongation cycle in the patient, there is a failure to recruit the _______ at the correct site in the mRNA sequence.This results in the translation of an abnormally long peptide.

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Definitions:

Tax Bills

Statements of money owed to the government as a result of taxation.

Marginal Tax Rate

The rate at which the next dollar of taxable income will be taxed, a concept crucial in understanding progressive taxation systems.

Federal

Pertaining to the central government, as opposed to state or local governments, especially regarding its relationship with the states in a federal system of government.

Taxable Personal Income

The amount of an individual's income that is subject to taxation after all deductions and exemptions, according to the governing tax laws.