Gain of Function Mutations

question 55

Multiple Choice

Gain of function mutations

• A) are dominant mutations that are expressed in wild-type cells.
• B) are dominant mutations that are expressed in mutant cells.
• C) are the cause of continuous division in cancer cells.
• D) can be analyzed only under restrictive conditions.
• E) are expressed only with the appropriate environmental signals.

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Definitions:

Maximum Likelihood

The maximum likelihood is an approach used to estimate parameter values for a statistical model. Maximum likelihood and the similar Bayesian method are used in phylogeny reconstruction to find the tree topologies that are most likely, given a precise model for molecular evolution and a particular data set.

Distance Methods

A set of techniques used in molecular biology and phylogenetics to estimate genetic differences and infer evolutionary relationships between species based on genetic data.

Molecular Evolution

The process by which genetic material undergoes changes in its molecular structure and sequences over generations.

BRCA1 Gene

A gene that produces a protein responsible for repairing DNA, where mutations can lead to an increased risk of breast and ovarian cancer.