Children Born with Two Nonfunctional RB Genes Will Develop Retinoblastoma

question 107

Multiple Choice

Children born with two nonfunctional RB genes will develop retinoblastoma, a retinal tumor.The mutations that result in nonfunctional RB protein include the following types of mutations.Which mutation represents a SNP in the coding sequence of the gene?

• A) Nonsense mutation
• B) Frame-shift mutation
• C) Intron mutation
• D) In-frame deletion
• E) Promoter mutation

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Definitions:

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