Which Event Would Lead to a Reduction in Gene Expression

question 116

Multiple Choice

Which event would lead to a reduction in gene expression?

• A) Mutation of the DNA-binding domain of an activator, changing its shape
• B) Mutation of the binding site of a co-repressor molecule within a repressor protein
• C) Removal of all methylation marks from a region of DNA
• D) Remodeling of the chromatin environment, resulting in removal of histone octamers from a gene's promoter region
• E) Mutation of a TATA box to create a tighter binding of RNA polymerase to the DNA

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Definitions:

Matching Principle

An accounting principle that dictates expenses should be recognized in the same period as the revenues they helped generate.

Depletion

The accounting process of allocating the cost of natural resources over their productive life, used in industries like mining, timber, and oil extraction.

Estimated Lives

The expected period over which an asset is anticipated to be usable by the company, affecting depreciation and amortization calculations.

Salvage Values

The estimated residual value of an asset at the end of its useful life, determining its value when it can no longer be used for its primary purpose.