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The Model Virus Bacteriophage λ (Lambda) Has Been Used Extensively

question 97

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The model virus bacteriophage λ (lambda) has been used extensively to study the lysogenic mechanism.The virus genome includes genes that encode the regulator proteins cI and Cro, which compete for specific promotors on the viral DNA-including their own promotors.Cro and cI have opposite effects on each promotor: cI represses the expression of genes involved in the lytic cycle and promotes expression of genes involved in lysogeny, whereas Cro does the opposite.Suppose a mutation in Cro increases its expression.This mutation would make entering lysogeny _______ likely.A mutation that increases the expression of cI would have _______ effect on the likelihood of the virus entering lysogeny.


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