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A Hypothetical Drug Has a Side Effect of Increasing Blood

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A hypothetical drug has a side effect of increasing blood pressure.Individuals who are homozygous for G at SNP 1 break down this drug faster than average.Individuals who are homozygous for A at SNP 2 break down this drug slower than average.The effects of these two SNPs roughly cancel each other out, such that homozygotes at both SNPs generally have average rates of breakdown of the enzyme.Which combination of genotypes is most likely to put an individual at risk for having the side effect? (Note: The genotype of SNP 1 is listed first, followed by that of SNP 2.)

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Definitions:

Perfectly Competitive

Refers to markets that meet the criteria of perfect competition, ensuring no single buyer or seller can influence prices or market conditions.

Diminishing Returns

A decrease in the marginal output of a production process as the amount of a single factor of production is incrementally increased, holding all other factors constant.

Value Added

The amount by which the value of goods or services is increased at each stage of its production, exclusive of initial costs.

Marginal Product

The increase in output resulting from a one-unit increase in the amount of a single input, holding all other inputs constant.

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