A Hypothetical Drug Has a Side Effect of Increasing Blood

question 39

Multiple Choice

A hypothetical drug has a side effect of increasing blood pressure.Individuals who are homozygous for G at SNP 1 break down this drug faster than average.Individuals who are homozygous for A at SNP 2 break down this drug slower than average.The effects of these two SNPs roughly cancel each other out, such that homozygotes at both SNPs generally have average rates of breakdown of the enzyme.Which combination of genotypes is most likely to require an individual to take a larger than average dose of the drug to get the desired effect? (Note: The genotype of SNP 1 is listed first, followed by that of SNP 2.)

• A) GG, AA
• B) GG, AG
• C) GC, AA
• D) GC, AG
• E) GC, GG

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Definitions:

Asymmetric Information

A situation in markets where one party to a transaction has more or better information than the other, often leading to inefficiencies or unfair advantages.

Health Care Suppliers

Entities that provide medical goods and services including hospitals, clinics, pharmacies, and manufacturers of medical equipment.

Demand

The willingness and capacity of customers to buy products and services at specific prices.

Supply

The total amount of a good or service that producers are willing and able to sell at a given price level.