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Suppose three sibling species of frogs have the following DNA sequences at a portion of a gene: Species 1: AGTCTAGATCGCGGTCG
Species 2: AGTCGATCGCGGACG
Species 3: TGTCTAGATCACGGTCG
Recall that the observed number of mutations can differ from the total number of actual substitutions that occurred in pairwise sequence comparisons.If we assume that a gap of any length is equivalent to three nucleotide substitutions, how many substitutions have occurred between species 1 and species 3?
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