Consider a hypothetical enzyme-coding gene and sequences of the gene from several species of rodents.The figure shows the rates of nonsynonymous and synonymous substitutions for each of four regions of the gene. 
Which region is under the strongest purifying selection?
Definitions:
Organizational Culture Artifact
Tangible or visibly recognizable elements within an organization that reflect its culture, such as its language, rituals, symbols, stories, and physical arrangements.
Ceremony
A formal event conducted on important occasions, often involving ritualistic procedures or celebrations.
Ritual
A series of actions or type of behavior regularly and invariably followed by individuals, often with symbolic meaning.
Culture Clash
Occurs when individuals or groups from different cultural backgrounds come into conflict due to differing beliefs, values, norms, or behaviors.
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