You Grow Some B Cells in Laboratory Culture and Find

question 139

Multiple Choice

You grow some B cells in laboratory culture and find that they are expressing IgM, which reacts to sheep red blood cells.Later you test the growth medium and find almost no IgM, but a large amount of IgG.The IgG also reacts to sheep red blood cells.If you were to analyze the cells before and after the switch in antibody, you would see that the IgG being produced by the B cells have a different _______ when compared to the IgM.

• A) light chain variable region
• B) heavy chain variable region
• C) MHC I
• D) antigen recognition site
• E) heavy chain constant region

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