A Mouse with an Ob/ob Genotype Lacks Functional Leptin

question 219

Multiple Choice

A mouse with an ob/ob genotype lacks functional leptin.A second mouse with a db/db genotype lacks functional leptin receptors.Both mice have been allowed to feed at will.It is most likely that

• A) the ob/ob mouse will be obese and the db/db mouse will be thin.
• B) the ob/ob mouse will be thin and the db/db mouse will be obese.
• C) the ob/ob mouse will be obese and the db/db mouse will be a normal weight.
• D) both the ob/ob mouse and the db/db mouse will be thin.
• E) both the ob/ob mouse and the db/db mouse will be obese.

---

Definitions:

Prefrontal Lobotomy

A surgical procedure used in the past to treat certain mental disorders, involving severing connections in the brain's prefrontal cortex.

Trephining

An ancient medical procedure that involves drilling or scraping a hole into the human skull to treat health issues, believed to release evil spirits or treat brain-related ailments in prehistoric times.

Psychosurgery

A type of brain surgery, such as lobotomy, used to treat mental disorders by removing or altering tissues of the brain.

Lobotomy

A neurosurgical procedure, historically used to treat mental disorders by severing connections in the brain's prefrontal cortex.