Refer to the Table

question 138

Multiple Choice

Refer to the table.In mice, a single-gene mutation can lead to obesity.The Ob gene codes for the protein leptin.The recessive ob allele is a loss-of-function allele, so ob/ob mice do not produce leptin, and they become obese.In an experiment, leptin was injected into ob/ob and Ob/Ob (wild-type) mice daily.The data in the table below were collected before the injections began (baseline) and 10 days later.(Assume that the Ob allele is dominant.) What conclusion can be drawn from the data in the table?

• A) The mutant mice gain more weight, but they do not eat more, than wild-type mice.
• B) Though a mutant mouse that is unable to produce leptin eats more than a wild-type mouse, injecting leptin causes the mutant mouse to eat normally.
• C) When leptin levels are increased above normal, a mouse eats less and loses weight.
• D) Metabolic rates are lower in wild-type mice than in mutant mice.
• E) Metabolic rates in mutant mice are negatively correlated with their body temperatures.

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Definitions:

Unsanitary Conditions

Poor or inadequate cleanliness practices that increase the risk of spreading diseases or infections, particularly in populated areas or communities.

Horizontal Gene Transfer

The exchange of genetic information between single-celled and/or multi-celled organisms that occurs via routes excluding the direct descent of DNA from parents to their progeny.

Antibiotic Resistance

The ability of bacteria to develop resistance to antibiotics, making them harder to eliminate and treat.

Bacteria

Single-celled microorganisms that come in various shapes and can inhabit a wide range of environments, including extreme conditions.