The Clinical Laboratory and Standards Institute (CLSI) Recommends That All

question 37

Multiple Choice

The Clinical Laboratory and Standards Institute (CLSI) recommends that all patient specimens are delivered to the laboratory no more than 2 hours after collection to reduce preexamination variables caused by cellular action and the effects of prolonged exposure of specimens to room temperatures, such as:

• A) glycolysis caused by cells' use of glucose; hemolysis and leakage of potassium from the cells into the plasma or serum; the destruction of coagulation factors from exposure to room temperatures.
• B) leakage of coagulation factors into the serum or plasma by cellular metabolism; increased potassium values caused by exposure to room temperature; increased glucose values caused by cellular metabolism.
• C) glycolysis caused by leakage from cells; increased levels of coagulation factors caused by prolonged exposure to room temperatures; decreased potassium levels caused by cellular metabolism.
• D) glycolysis caused by exposure to room temperatures; hemolysis and leakage of coagulation factors from the cells; decreased potassium levels in the serum and plasma by cellular utilization.

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