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Metabolic Tolerance
An adaptive process where increased metabolic activity reduces the effective concentration of a substance, such as a drug, requiring higher doses to achieve the same effect.
Synaptic Fatigue
A temporary decrease in synaptic efficacy after sustained activity, often resulting from the depletion of neurotransmitter supplies.
Cellular Tolerance
Cellular tolerance is a physiological adaptation where increased exposure to a substance, like a drug, leads to a decrease in the substance's effect on cells or tissues.
Intoxicated
The condition of having physical and mental faculties impaired by an excess of alcoholic drink or any substance, leading to altered mood, behavior, and coordination.
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