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A Study Was Completed to Determine Whether Early Alterations in Glutamate

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A study was completed to determine whether early alterations in glutamate signaling, via daily injections of the glutamate agonist, domoic acid (DOM) , during a critical period of CNS development, would result in temporal memory deficits (Robbins, et. al, 2013) . Analyses revealed that DOM-treated females demonstrated temporal memory dysfunction, as evidenced in a significantly lower proportion of total exploratory behaviour directed toward the remote objects. This work demonstrated that glutamate is important in


Definitions:

Interrupted Time Series Design

A quasi-experimental design in which observations are made over time both before and after an intervention.

Quasi-experimental Design

An empirical study used to estimate the causal impact of an intervention, lacking random assignment.

Hamburgers Sold

A numerical measure representing the quantity of hamburgers sold within a specific time frame, often used in business and marketing research.

Sequential Method

A combination of the cross-sectional and longitudinal design to study developmental research questions.

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