Isosorbide Dinitrate Is a Long-Acting Nitrate Given Twice Daily

question 4

Multiple Choice

Isosorbide dinitrate is a long-acting nitrate given twice daily. The schedule for administration is 7 a.m. and 2 p.m. because:

• A) Long-acting forms have a higher risk for toxicity.
• B) Orthostatic hypotension is a common adverse effect.
• C) It must be taken with milk or food.
• D) Nitrate tolerance can develop.

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