Carbamazepine Has a Black Box Warning Recommending Testing for the HLA-B*1502

question 4

Multiple Choice

Carbamazepine has a Black Box Warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to:

• A) Decreased effectiveness of carbamazepine in treating seizures in Asian patients with the HLA-B*1502 allele
• B) Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele
• C) Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele
• D) Patients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepine

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