Drugs Are Metabolized Mainly by the Liver Via Phase I

question 31

Multiple Choice

Drugs are metabolized mainly by the liver via phase I or phase II reactions. The purpose of both of these types of reactions is to:

• A) Inactivate prodrugs before they can be activated by target tissues
• B) Change the drugs so they can cross plasma membranes
• C) Change drug molecules to a form that an excretory organ can excrete
• D) Make these drugs more ionized and polar to facilitate excretion

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Definitions:

Independent Events

Events whose outcome or occurrence does not affect each other.

P(A ∩ B)

The probability of the intersection of events A and B, indicating the likelihood of both events occurring simultaneously.

P(B)

The probability notation representing the likelihood of event B occurring.

Indian Slave Trade

The historical practice of enslavement and trade of indigenous peoples of the Americas, especially prevalent during the European colonization era.