Canine Phosphofructokinase (PFK) Deficiency Afflicts Springer Spaniels, Affecting an Estimated

question 54

Multiple Choice

Canine phosphofructokinase (PFK) deficiency afflicts Springer spaniels, affecting an estimated 10 percent of the breed. Given its critical role in glycolysis, one implication of the genetic defect resulting in PFK deficiency in dogs is ________.

• A) early embryonic mortality
• B) elevated blood-glucose levels in the dog's blood
• C) an intolerance for exercise
• D) a reduced life span

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Definitions:

Glucagon

A hormone produced by the pancreas that raises blood glucose levels by promoting the conversion of stored glycogen into glucose in the liver.

Insulin

A substance created by the pancreas that controls the levels of sugar in the blood by helping glucose enter the body's tissues.

Fasting

The act of willingly refraining from some or all food, drink, or both, for a period of time.

Breakfast

The first meal of the day, usually eaten in the morning, considered important for providing the necessary energy and nutrients after an overnight fast.