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How Might a Change of One Amino Acid at a Site

question 24

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How might a change of one amino acid at a site, distant from the active site of an enzyme, alter an enzyme's substrate specificity?

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Definitions:

Clavicle

A long bone that serves as a strut between the shoulder blade and the sternum or breastbone, commonly known as the collarbone.

Scapula

The scapula, or shoulder blade, is a large, flat, triangular bone located in the upper back on each side of the vertebral column.

Humerus

The long bone in the upper arm that runs from the shoulder to the elbow, connecting the scapula to the bones of the forearm.

Xiphoid Process

The smallest and lowermost part of the sternum, varying in shape and size, often cartilaginous in early life before ossifying in adulthood.

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