Normal Hemoglobin Is a Tetramer, Consisting of Two Molecules of β

question 11

Multiple Choice

Normal hemoglobin is a tetramer, consisting of two molecules of β hemoglobin and two molecules of α hemoglobin. In sickle-cell disease, as a result of a single amino acid change, the mutant hemoglobin tetramers associate with each other and assemble into large fibers. Based on this information alone, we can conclude that sickle-cell hemoglobin exhibits ________.

• A) only altered primary structure
• B) only altered secondary structure
• C) only altered tertiary structure
• D) only altered quaternary structure
• E) altered primary structure and altered quaternary structure; the secondary and tertiary structures may or may not be altered

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Definitions:

FIFO

An accounting method for inventory valuation where the first items purchased or produced are the first ones used or sold.

Average Cost

A method of inventory valuation where the cost of goods sold and ending inventory are calculated based on the average cost of all similar items held in inventory.

Inventory System

The method a company uses to manage and track its inventory, ensuring the right quantity of products at the right time and minimizing costs.

Perpetual

A system of inventory management wherein updates are made continuously to the inventory accounts after each purchase or sale.