Normal Hemoglobin Is a Tetramer, Consisting of Two Molecules of β

question 11

Multiple Choice

Normal hemoglobin is a tetramer, consisting of two molecules of β hemoglobin and two molecules of α hemoglobin. In sickle-cell disease, as a result of a single amino acid change, the mutant hemoglobin tetramers associate with each other and assemble into large fibers. Based on this information alone, we can conclude that sickle-cell hemoglobin exhibits ________.

• A) only altered primary structure
• B) only altered secondary structure
• C) only altered tertiary structure
• D) only altered quaternary structure
• E) altered primary structure and altered quaternary structure; the secondary and tertiary structures may or may not be altered

---

Definitions:

Subdivisions

The act of dividing land into plots or parcels for the purpose of sale, lease, or development.

Applicability

The relevance or suitability of a law, regulation, or principle in a specific context or situation.

Zoning Ordinance

Regulations set by local governments determining how land within their jurisdiction can be used, affecting the development and use of properties.

Occupancy

Occupancy refers to the use or inhabitance of a space, such as a building or land, typically governed by legal or contractual terms.