Which of the Following Would Provide a Synthesis of Aspirin

question 76

Multiple Choice

Which of the following would provide a synthesis of aspirin, o-CH₃COOC₆H₄COOH?

• A) C₆H₅COOH,CH₃COOH,AlCl₃,heat;then H₂O
• B) CH₃COOC₆H₅,CO₂,heat;then H₃O⁺
• C) CH₃COOC₆H₅,HCOOC₂H₅,C₂H₅O^-;then H₃O⁺;then OH^-
• D) C₆H₅OH,CO₂,H₃O⁺;separate isomers;then CH₃COOH,AlCl₃
• E) C₆H₅OH,OH^-,CO₂,heat,pressure;then H₃O⁺;then (CH₃CO)₂O

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