Which Best Describes the Mechanism of OH--Mediated Denaturation of DNA

question 21

Multiple Choice

Which best describes the mechanism of OH--mediated denaturation of DNA?

• A) OH- disrupts the H-bonding between the nitrogenous bases of opposing DNA strands.
• B) OH- hydrolyzes the phosphodiester linkages between nucleotides.
• C) The hydroxyl ions attract the unpaired electrons of the amino groups attached to the nitrogenous bases.
• D) Alkali tends to increase the melting temperature of DNA.

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