RFLP Linkage Analysis Followed by Chromosome Walking Is Used to Find

question 65

Multiple Choice

RFLP linkage analysis followed by chromosome walking is used to find disease-causing genes. Which of the following would be a good indication that the disease-causing gene has been found by this analysis?

• A) The gene is at least one cM from the RFLP.
• B) The gene is homozygous in the affected individual.
• C) The gene contains a nonsense mutation.
• D) The gene is heterozygous in the individual.
• E) The gene contains numerous polymorphisms.

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