It Is Sometimes Possible to Design a Degenerate Oligonucleotide Probe

question 53

Multiple Choice

It is sometimes possible to design a degenerate oligonucleotide probe for screening a DNA library if the amino acid sequence of the protein is available. These probes are

• A) composed of a mixture of different oligonucleotide sequences.
• B) composed only of the most frequently used codon for each amino acid.
• C) completely random oligonucleotide sequences.
• D) small restriction enzyme fragments.

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Definitions:

External Validity

The extent to which the findings of a study can be generalized to other settings, populations, and times beyond the study conditions.

Independent Variable

A variable that is manipulated or changed in an experiment to see if it has an effect on the dependent variable.

Correlation Coefficient

A statistical measure that indicates the extent to which two or more variables fluctuate together, ranging from -1 to 1, where 1 means a perfect positive relationship, -1 means a perfect negative relationship, and 0 means no relationship.

Variables

Elements or factors that can change and affect the outcomes of scientific research or experiments.