Vector Development, Design of the Corrective Gene Construct, Proliferation and Maintenance

question 13

Multiple Choice

Vector development, design of the corrective gene construct, proliferation and maintenance of target cells, efficient transfection and transport of nucleic acid to the nucleus for integration into the genome, and expansion of engineered cells and implantation into the patient are all examples of

• A) challenges to successful gene therapy.
• B) techniques used to study developmental regulation.
• C) protocols used in the production of transgenic and chimeric mice.
• D) problems encountered in the development of pharmaceuticals.

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Definitions:

Glucose Metabolism

The process by which cells convert glucose into energy, involving pathways like glycolysis and the citric acid cycle.

Metabolic Syndrome

A cluster of conditions—increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels—that occur together, increasing your risk of heart disease, stroke, and diabetes.

Type 1 Diabetes

An autoimmune condition where the pancreas produces little or no insulin, requiring daily insulin administration for management.

Cardiovascular Disease

This category includes medical conditions impacting the heart or the circulatory system, like coronary artery disease, hypertension, and strokes.